National Heart, Lung, and Blood Institute: What Are Thrombocythemia and Thrombocytosis? This website uses cookies to improve your experience while you navigate through the website. They are sometimes called "normal" values. My platelet count is low. Some people may also notice cold fingertips, along with the tingling sensation. Each component of the clotting process must be present, activated at the right time, and functioning properly for adequate clotting. Thrombocytes have a short life span of about eight to ten days, but the bone marrow continues to produce new blood platelets. There are actually over 10 factors. The treatment is aimed at resolving the underlying condition with the help of drugs. If your condition is mild and your platelet count is only slightly low, you may not require any treatment. Let's learn about the contributory factors for an abnormally high platelet count. Bacterial infections may be pneumonia, pyelonephritis, purulent arthritis, osteomyelitis, chronic wound infections, tuberculosis, among others. Copyright © Health Hearty &, Inc. Some research shows that essential thrombocythemia is diagnosed in only about 6 persons per 100,000 people in one year. Often, abnormal results will prompt additional testing. Platelet abnormalities during colonic inflammation.

Idiopathic thrombocytopenia (ITP), also known as immune thrombocytopenic purpura, is the result of antibody production against platelets. Video Credit: American Society of Hematology, © 2001-2020 by American Association for Clinical Chemistry. Medical College of Virginia, Virginia Commonwealth University. Too many platelets can lead to certain conditions, including stroke, heart attack, or a clot in the blood vessels.

(July 17, 2010) Mayo Clinic. The reference ranges1 provided here represent a theoretical guideline that should not be used to interpret your test results. 2010;27(5):413-9.  doi:10.3109/08880011003739455, Oida T, Kano H, Mimatsu K, et al. In general, the risk is greatest in the month after splenectomy. Normal count is in the range of 150,000 to 450,000 platelets per microlitre of blood. An increased production of platelets can also be caused by other disorders. This category only includes cookies that ensures basic functionalities and security features of the website. In some people, it is also due to hemorrhage and/or iron deficiency. This condition affects about 2 to 3 people in 100,000.

Your healthcare practitioner may repeat the test and may look at results from prior platelet counts. Increased platelet count has also been observed in approximately 66% of patients with polycythemia vera. For more details, see our Privacy Policy. Your email address will not be published. While tests of coagulation, including the platelet count, have frequently been used to identify patients with an increased risk of peri-operative bleeding, results have been equivocal. This is actually the body’s reaction to deal with the sudden happenings in the body.

When there is an injury to a blood vessel or tissue and bleeding begins, platelets help stop bleeding in three ways. This would help confirm whether platelets might truly be low in number or have clumped together, in addition to assessing their appearance with regards to size and granularity. Infection. A few examples include: Some people have platelets that tend to "pool" or collect (sequester) in their spleen, resulting in a low platelet count. Yuko, S. et. Pagana, Kathleen D. & Pagana, Timothy J.

Please consult your healthcare provider.

Accessed Feb 2012. Accessed Feb 2012. Surgery, especially splenectomy (removal of the spleen).

High platelet count. Normal levels of platelets in the blood is about 150-450×109 / L of blood. Permanent thrombocytosis after splenectomy should give pause for thought about the existence of myeloproliferative disorder or any condition that may have developed like hemolysis or ineffective erythropoiesis. This enzyme converts prothrombin present in blood into thrombin. The health care professionals would want to know the history about the past surgeries, diseases, etc.

Polycythemia vera is a condition that is characterized by increased production of platelets. Essential thrombocytosis, or primary thrombocythemia is a chronic disease characterized as a myeloproliferative neoplasm showing an enlargement in the total number of blood platelets.